Prothrombin Fragment 2 (C-Term) Antikörper

Produktnummer ABIN3042926

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-Prothrombin Fragment 2 Antikörper wird verwendet zum Nachweis von Prothrombin Fragment 2 in Proben von Ratte. Er wurde validiert für WB.

Kurzübersicht für Prothrombin Fragment 2 (C-Term) Antikörper (ABIN3042926)

Target: Prothrombin Fragment 2

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Prothrombin/F2 Antibody

Sequenz: THVFRLKRWM QKV

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Prothrombin/F2 Antibody. Tested in WB applications. This antibody reacts with Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of rat Prothrombin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Rat

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen

Shen, Fang, Lv, Pei, Wang, Jiang, Ding: "Heparin impairs angiogenesis through inhibition of microRNA-10b." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26616-27, (2011) (PubMed).

Antigendetails

Target: Prothrombin Fragment 2

Hintergrund:

Background: F2 (Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. Royle et al. (1987) assigned the gene for human prothrombin (F2) to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII (F8), and XIII (F13A1). Thrombin also inhibits coagulation by activating protein C.

Gene Full Name: coagulation factor II(thrombin)

Sequence Similarities: Belongs to the peptidase S1 family.

Molekulargewicht: 100 kDa

Gen-ID: 29251

UniProt: P18292