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AQP6 Antikörper (C-Term)

AQP6 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042906
  • Target Alle AQP6 Antikörper anzeigen
    AQP6 (Aquaporin 6, Kidney Specific (AQP6))
    Bindungsspezifität
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 264-282, C-Term
    Reaktivität
    • 13
    • 5
    • 4
    • 3
    • 3
    Human
    Wirt
    • 14
    Kaninchen
    Klonalität
    • 14
    Polyklonal
    Konjugat
    • 8
    • 3
    • 2
    • 1
    Dieser AQP6 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 9
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    Anti-Aquaporin 6/AQP6 Antibody Picoband®
    Sequenz
    EPLKKESQPG SGAVEMESV
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-Aquaporin 6/AQP6 Antibody (ABIN3042906). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 6.
    Isotyp
    IgG
    Top Product
    Discover our top product AQP6 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. "Entrez Gene: Aquaporin 6, kidney specific". Retrieved 2012-04-10 2. Ma, T., Yang, B., Umenishi, F., Verkman, A. S. Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chromosome locus 12q13. Genomics 43: 387-389, 1997. 3. Liu, K., Kozono, D., Kato, Y., Agre, P., Hazama, A., Yasui, M. Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution. Proc. Nat. Acad. Sci. 102: 2192-2197, 2005.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    AQP6 (Aquaporin 6, Kidney Specific (AQP6))
    Andere Bezeichnung
    AQP6 (AQP6 Produkte)
    Hintergrund

    Synonyms: Aquaporin-6,AQP-6,Aquaporin-2-like,Kidney-specific aquaporin,hKID,AQP6,AQP2L,

    Background: Aquaporin 6, kidney specific is a protein in humans that is encoded by the AQP6 gene. The aquaporins (AQPs) are a family of water-transporting proteins that facilitate osmotically driven water movement across cell plasma membranes. Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Unlike other aquaporins, AQP6 functions not as a water channel but as an anion-selective channel. Single-channel analyses have shown AQP6 to flicker rapidly between closed and open status.

    Molekulargewicht
    142 kDa
    UniProt
    Q13520
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