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AQP6 Antikörper (C-Term)

Dieses Anti-AQP6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von AQP6 in WB und IHC. Geeignet für Human.
Produktnummer ABIN3042906

Kurzübersicht für AQP6 Antikörper (C-Term) (ABIN3042906)

Target

Alle AQP6 Antikörper anzeigen
AQP6 (Aquaporin 6, Kidney Specific (AQP6))

Reaktivität

  • 14
  • 5
  • 4
  • 3
  • 3
Human

Wirt

  • 14
  • 1
Kaninchen

Klonalität

  • 15
Polyklonal

Konjugat

  • 9
  • 3
  • 2
  • 1
Dieser AQP6 Antikörper ist unkonjugiert

Applikation

  • 12
  • 10
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 264-282, C-Term

    Verwendungszweck

    Anti-Aquaporin 6/AQP6 Antibody Picoband®

    Sequenz

    EPLKKESQPG SGAVEMESV

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Aquaporin 6/AQP6 Antibody (ABIN3042906). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 6.

    Isotyp

    IgG
  • Applikationshinweise

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. "Entrez Gene: Aquaporin 6, kidney specific". Retrieved 2012-04-10 2. Ma, T., Yang, B., Umenishi, F., Verkman, A. S. Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chromosome locus 12q13. Genomics 43: 387-389, 1997. 3. Liu, K., Kozono, D., Kato, Y., Agre, P., Hazama, A., Yasui, M. Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution. Proc. Nat. Acad. Sci. 102: 2192-2197, 2005.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    AQP6 (Aquaporin 6, Kidney Specific (AQP6))

    Andere Bezeichnung

    AQP6

    Hintergrund

    Synonyms: Aquaporin-6,AQP-6,Aquaporin-2-like,Kidney-specific aquaporin,hKID,AQP6,AQP2L,

    Background: Aquaporin 6, kidney specific is a protein in humans that is encoded by the AQP6 gene. The aquaporins (AQPs) are a family of water-transporting proteins that facilitate osmotically driven water movement across cell plasma membranes. Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Unlike other aquaporins, AQP6 functions not as a water channel but as an anion-selective channel. Single-channel analyses have shown AQP6 to flicker rapidly between closed and open status.

    Molekulargewicht

    142 kDa

    UniProt

    Q13520
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