EGR2 Antikörper (N-Term)

Produktnummer ABIN3042850

Produktdetails anti-EGR2 Antikörper

Target: EGR2 (Early Growth Response 2 (EGR2))

Bindungsspezifität: AA 153-168, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EGR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for E3 SUMO-protein ligase EGR2(EGR2) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: TMSQTQPDLD HLYSPP

Kreuzreaktivität (Details): Predicted Cross Reactivity: rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for E3 SUMO-protein ligase EGR2(EGR2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: early growth response 2
Protein Name: E3 SUMO-protein ligase EGR2

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human EGR2(153-168aa TMSQTQPDLDHLYSPP), different from the related rat and mouse sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Predicted Species: Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu EGR2

Target: EGR2 (Early Growth Response 2 (EGR2))

Andere Bezeichnung: EGR2 (EGR2 Produkte)

Synonyme: AT591 antikoerper, CMT1D antikoerper, CMT4E antikoerper, KROX20 antikoerper, Egr-2 antikoerper, Krox-20 antikoerper, Krox20 antikoerper, NGF1-B antikoerper, Zfp-25 antikoerper, Zfp-6 antikoerper, KRX-20 antikoerper, cb427 antikoerper, egr2 antikoerper, id:ibd5073 antikoerper, krox20 antikoerper, krx20 antikoerper, wu:fb71h10 antikoerper, zgc:92210 antikoerper, frb35 antikoerper, early growth response 2 antikoerper, early growth response 2b antikoerper, early growth response 2a antikoerper, EGR2 antikoerper, Egr2 antikoerper, egr2b antikoerper, egr2a antikoerper

Hintergrund: Early growth response protein 2, also called EGR2 or E3 SUMO-protein ligase EGR2, is a protein that in humans is encoded by the EGR2 gene. This gene is mapped to 10q21.3. The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D(CMT1D), Charcot-Marie-Tooth disease type 4E(CMT4E), and with Dejerine-Sottas syndrome(DSS). E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.

Synonyms: AT591 antibody|CMT1D antibody|CMT4E antibody|DKFZp686J1957 antibody|E3 SUMO-protein ligase EGR2 antibody|Early growth response 2 antibody|Early growth response protein 2 antibody|EGR-2 antibody|egr2 antibody|EGR2_HUMAN antibody|FLJ14547 antibody|KROX 20 Drosophila homolog antibody|Krox 20 homolog Drosophila antibody|KROX-20, Drosophila, homolog(early growth response-2) antibody|KROX20 antibody|Krox20 protein antibody|Zinc finger protein Krox-20 antibody

UniProt: P11161