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SELENBP1 Antikörper (Middle Region)

SELENBP1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042829
  • Target Alle SELENBP1 Antikörper anzeigen
    SELENBP1 (Selenium Binding Protein 1 (SELENBP1))
    Bindungsspezifität
    • 14
    • 7
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 226-240, Middle Region
    Reaktivität
    • 49
    • 35
    • 29
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 4
    Kaninchen
    Klonalität
    • 45
    • 4
    Polyklonal
    Konjugat
    • 19
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SELENBP1 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 18
    • 12
    • 12
    • 9
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    Anti-SBP/SELENBP1 Antibody Picoband®
    Sequenz
    SHLYVWDWQR HEIVQ
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-SBP/SELENBP1 Antibody (ABIN3042829). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human Selenium Binding Protein 1.
    Isotyp
    IgG
    Top Product
    Discover our top product SELENBP1 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. Chang, P. W. G., Tsui, S. K. W., Liew, C., Lee, C., Waye, M. M. Y., Fung, K. Isolation, characterization, and chromosomal mapping of a novel cDNA clone encoding human selenium binding protein. J. Cell. Biochem. 64: 217-224, 1997. 2. Okunuki, Y., Usui, Y., Takeuchi, M., Kezuka, T., Hattori, T., Masuko, K., Nakamura, H., Yudoh, K., Usui, M., Nishioka, K., Kato, T. Proteomic surveillance of autoimmunity in Behcet's disease with uveitis: selenium binding protein is a novel autoantigen in Behcet's disease. Exp. Eye Res. 84: 823-831, 2007.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    SELENBP1 (Selenium Binding Protein 1 (SELENBP1))
    Andere Bezeichnung
    SELENBP1 (SELENBP1 Produkte)
    Hintergrund

    Synonyms: Selenium-binding protein 1,56 kDa selenium-binding protein,SBP56,SP56,SELENBP1,SBP,

    Tissue Specificity: Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients. .

    Background: Selenium-binding protein 1, also known as SELENBP1 or SBP is a protein that in humans is encoded by the SLELNBP1 gene. This gene is mapped to 1q21.3. This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation.

    Sequence Similarities: Belongs to the PIAS family.

    Molekulargewicht
    57 kDa
    UniProt
    Q13228
    Pathways
    Brown Fat Cell Differentiation
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