SERPINC1 Antikörper (N-Term)

Produktnummer ABIN3042828

Dieses Anti-SERPINC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SERPINC1 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SERPINC1 Antikörper (N-Term) (ABIN3042828)

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SERPINC1 Antikörper

Bindungsspezifität: AA 93-107, N-Term

Verwendungszweck: Anti-Antithrombin III/SERPINC1 Antibody Picoband®

Sequenz: TFYQHLADSK NDNDN

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Antithrombin III/SERPINC1 Antibody (ABIN3042828). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Antithrombin III, different from the related mouse and rat sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Baud, O., Picard, V., Durand, P., Duchemin, J., Proulle, V., Albenc-Gelas, M., Devictor, D., Dreyfus, M. Intracerebral hemorrhage associated with a novel antithrombin gene mutation in a neonate. J. Pediat. 139: 741-743, 2001. 2. Fischer, A. M., Cornu, P., Sternberg, C., Meriane, F., Dautzenberg, M. D., Chafa, O., Beguin, S., Desnos, M. Antithrombin III Alger: a new homozygous AT III variant. Thromb. Haemost. 55: 218-221, 1986.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SERPINC1

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Andere Bezeichnung: SERPINC1

Hintergrund:

Synonyms: Antithrombin-III,ATIII,Serpin C1,SERPINC1,AT3,PRO0309,

Tissue Specificity: Found in plasma.

Background: Serpin peptidase inhibitor, clade C (antithrombin), member 1, also known as Antithrombin III (AT3) is the most important inhibitor of thrombin OMBIN III and other coagulation proteinases. This gene is mapped to 1q25.1. The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

Sequence Similarities: Belongs to the serpin family.

Molekulargewicht: 57 kDa

UniProt: P01008