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Nerve Growth Factor Antikörper (AA 122-241)

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Nerve Growth Factor in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 10+ Publikationen erwähnt.
Produktnummer ABIN3042793

Kurzübersicht für Nerve Growth Factor Antikörper (AA 122-241) (ABIN3042793)

Target

Alle Nerve Growth Factor (NGF) Antikörper anzeigen
Nerve Growth Factor (NGF)

Reaktivität

  • 103
  • 57
  • 55
  • 8
  • 7
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 95
  • 32
  • 10
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 77
  • 69
  • 1
Polyklonal

Konjugat

  • 96
  • 15
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Nerve Growth Factor Antikörper ist unkonjugiert

Applikation

  • 84
  • 53
  • 48
  • 30
  • 28
  • 16
  • 12
  • 8
  • 7
  • 6
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 122-241

    Verwendungszweck

    Anti-Beta-nerve growth factor NGF Antibody

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Beta-nerve growth factor NGF Antibody (ABIN3042793). Tested in ELISA, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E. coli-derived human NGFB recombinant protein (Position: S122-A241).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, -
    ELISA, 0.1-0.5 μg/mL, -

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide. Carrier free (No BSA) form available in stock. If you want this antibody carrier free please specify Carrier Free or No BSA in your order note.

    Konservierungsmittel

    Sodium azide, Without preservative

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Fan, Xiong, Fu, Xu, Wang, Chen, Xia, Peng, Ye, Wang, Zhang, Ye et al.: "Polyaniline promotes peripheral nerve regeneration by enhancement of the brain‑derived neurotrophic factor and ciliary neurotrophic factor expression and activation of the ERK1/2/MAPK signaling ..." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 7534-7540, (2018) (PubMed).

    Luo, Liu, Chen, Wang, Zeng, Chen, Cheng et al.: "Nerve growth factor and inducible nitric oxide synthase expression in the mesencephalon and diencephalon, as well as visual- and auditory-related nervous tissues, in a macaque model of type 2 ..." in: Neural regeneration research, Vol. 7, Issue 4, pp. 302-7, (2015) (PubMed).

    Zhao, Chen, Shen, Zhao, Wang, Shi, Wang, Cui, Yan, Xue: "Transplantation of human umbilical cord blood mesenchymal stem cells to treat a rat model of traumatic brain injury." in: Neural regeneration research, Vol. 7, Issue 10, pp. 741-8, (2015) (PubMed).

    Lu, Liu, Zhu, Xu: "Expression of nerve growth factor and hypoxia inducible factor-1? and its correlation with angiogenesis in non-small cell lung cancer." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 3, pp. 359-62, (2014) (PubMed).

    Li, Ma, Yi, Wang, Li, Liu, Sun, Chen, Yu, Li, Chen, Zhou: "The interactions between nerve growth factor and gonadotrophins in bovine oviduct." in: Animal reproduction science, Vol. 149, Issue 3-4, pp. 117-23, (2014) (PubMed).

    Huang, Zhang, Xu, Li, Zhao: "Expression of nerve growth factor in the prostate of male rats in response to chronic stress and sympathetic denervation." in: Experimental and therapeutic medicine, Vol. 8, Issue 4, pp. 1237-1240, (2014) (PubMed).

    Li, Shu, Tang, Deng, Fu, Lv: "?-Nerve growth factor attenuates hepatocyte injury induced by D-galactosamine in vitro via TrkA NGFR." in: Molecular medicine reports, Vol. 8, Issue 3, pp. 813-7, (2013) (PubMed).

    Pu, Shi, Wang, Wang, Guo, Liu, Sun, Gao, Zhou: "Effects of minocycline on the expression of NGF and HSP70 and its neuroprotection role following intracerebral hemorrhage in rats." in: Journal of biomedical research, Vol. 25, Issue 4, pp. 292-8, (2013) (PubMed).

    Sun, Guo, Zheng, Zhang, Li, Liu, Yin, Yang, Shu: "Increased expression of TRPV1 in the cortex and hippocampus from patients with mesial temporal lobe epilepsy." in: Journal of molecular neuroscience : MN, Vol. 49, Issue 1, pp. 182-93, (2012) (PubMed).

    Orita, Koshi, Mitsuka, Miyagi, Inoue, Arai, Ishikawa, Hanaoka, Yamashita, Yamashita, Eguchi, Toyone, Takahashi, Ohtori: "Associations between proinflammatory cytokines in the synovial fluid and radiographic grading and pain-related scores in 47 consecutive patients with osteoarthritis of the knee." in: BMC musculoskeletal disorders, Vol. 12, pp. 144, (2012) (PubMed).

  • Target

    Nerve Growth Factor (NGF)

    Andere Bezeichnung

    NGF

    Hintergrund

    Synonyms: Beta-nerve growth factor,Beta-NGF,NGF,NGFB,

    Background: Nerve growth factor is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. the nucleotide sequence of human and mouse beta-NGF are very similar. the beta-subunits of nerve growth factor (NGFB) have been assigned to mouse chromosome 3 and human chromosome 1p22. The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1. A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception.

    Sequence Similarities: Belongs to the NGF-beta family.

    Molekulargewicht

    22 kDa

    UniProt

    P01138

    Pathways

    Regulation of Cell Size
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