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CSTA Antikörper (AA 8-98)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CSTA in WB, IHC, IF und ICC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN3042766

Kurzübersicht für CSTA Antikörper (AA 8-98) (ABIN3042766)

Target

Alle CSTA Antikörper anzeigen
CSTA (Cystatin A (Stefin A) (CSTA))

Reaktivität

  • 102
  • 27
  • 22
  • 2
Human

Wirt

  • 98
  • 37
Kaninchen

Klonalität

  • 97
  • 38
Polyklonal

Konjugat

  • 55
  • 16
  • 12
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CSTA Antikörper ist unkonjugiert

Applikation

  • 105
  • 74
  • 28
  • 26
  • 26
  • 25
  • 20
  • 20
  • 18
  • 17
  • 13
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 30
    • 16
    • 9
    • 7
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 8-98

    Verwendungszweck

    Anti-Cystatin A/CSTA Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Cystatin A/CSTA Antibody Picoband® (ABIN3042766). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Cystatin A recombinant protein (Position: E8-F98). Human Cystatin A shares 61.5% and 58.2% amino acid (aa) sequence identity with mouse and rat Cystatin A, respectively.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    1. Blaydon, D. C., Nitoiu, D., Eckl, K.-M., Cabral, R. M., Bland, P., Hausser, I., van Heel, D. A., Rajpopat, S., Fischer, J., Oji, V., Zvulunov, A., Traupe, H., Hennies, H. C., Kelsell, D. P. Mutations in CSTA, encoding cystatin A, underlie exfoliative ichthyosis and reveal a role for this protease inhibitor in cell-cell adhesion. Am. J. Hum. Genet. 89: 564-571, 2011. 2. Samuelsson, L., Stiller, C., Friberg, C., Nilsson, C., Inerot, A., Wahlstrom, J.Association analysis of cystatin A and zinc finger protein 148, two genes located at the psoriasis susceptibility locus PSORS5. J. Invest. Derm. 122: 1399-1400, 2004. 3. Vasilopoulos, Y., Walters, J., Cork, M. J., Duff, G. W., Sagoo, G. S., Tazi-Ahnini, R.Association analysis of the skin barrier gene cystatin A at the PSORS5 locus in psoriatic patients: evidence for interaction between PSORS1 and PSORS5.Europ. J. Hum. Genet. 16: 1002-1009, 2008.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    CSTA (Cystatin A (Stefin A) (CSTA))

    Andere Bezeichnung

    CSTA

    Hintergrund

    Synonyms: Cystatin-A,Cystatin-AS,Stefin-A,Cystatin-A, N-terminally processed,CSTA,STF1, STFA,

    Tissue Specificity: Expressed in the skin throughout the epidermis. .

    Background: Cystatin A also called Stefin A is a protein that in humans is encoded by the CSTA gene. Cystatin A is a cysteine proteinase inhibitor that belongs to family 1 of the cystatin superpamily. This gene was assigned to human chromosome 3q21.1. This is an intracellular thiol proteinase inhibitor. Cystatin A plays an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis. Stefins have been proposed as prognostic and diagnostic tools for cancer.

    Sequence Similarities: Belongs to the cystatin family.

    Molekulargewicht

    14 kDa

    Gen-ID

    1475

    UniProt

    P01040

    Pathways

    Response to Water Deprivation
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