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CSTA Antikörper (AA 8-98)

CSTA Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042766
  • Target Alle CSTA Antikörper anzeigen
    CSTA (Cystatin A (Stefin A) (CSTA))
    Bindungsspezifität
    • 17
    • 14
    • 9
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 8-98
    Reaktivität
    • 68
    • 20
    • 16
    Human
    Wirt
    • 75
    • 12
    Kaninchen
    Klonalität
    • 74
    • 13
    Polyklonal
    Konjugat
    • 34
    • 10
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CSTA Antikörper ist unkonjugiert
    Applikation
    • 67
    • 29
    • 24
    • 24
    • 24
    • 17
    • 13
    • 13
    • 11
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Verwendungszweck
    Anti-Cystatin A/CSTA Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-Cystatin A/CSTA Antibody Picoband® (ABIN3042766). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human Cystatin A recombinant protein (Position: E8-F98). Human Cystatin A shares 61.5% and 58.2% amino acid (aa) sequence identity with mouse and rat Cystatin A, respectively.
    Isotyp
    IgG
    Top Product
    Discover our top product CSTA Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    1. Blaydon, D. C., Nitoiu, D., Eckl, K.-M., Cabral, R. M., Bland, P., Hausser, I., van Heel, D. A., Rajpopat, S., Fischer, J., Oji, V., Zvulunov, A., Traupe, H., Hennies, H. C., Kelsell, D. P. Mutations in CSTA, encoding cystatin A, underlie exfoliative ichthyosis and reveal a role for this protease inhibitor in cell-cell adhesion. Am. J. Hum. Genet. 89: 564-571, 2011. 2. Samuelsson, L., Stiller, C., Friberg, C., Nilsson, C., Inerot, A., Wahlstrom, J.Association analysis of cystatin A and zinc finger protein 148, two genes located at the psoriasis susceptibility locus PSORS5. J. Invest. Derm. 122: 1399-1400, 2004. 3. Vasilopoulos, Y., Walters, J., Cork, M. J., Duff, G. W., Sagoo, G. S., Tazi-Ahnini, R.Association analysis of the skin barrier gene cystatin A at the PSORS5 locus in psoriatic patients: evidence for interaction between PSORS1 and PSORS5.Europ. J. Hum. Genet. 16: 1002-1009, 2008.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    CSTA (Cystatin A (Stefin A) (CSTA))
    Andere Bezeichnung
    CSTA (CSTA Produkte)
    Hintergrund

    Synonyms: Cystatin-A,Cystatin-AS,Stefin-A,Cystatin-A, N-terminally processed,CSTA,STF1, STFA,

    Tissue Specificity: Expressed in the skin throughout the epidermis. .

    Background: Cystatin A also called Stefin A is a protein that in humans is encoded by the CSTA gene. Cystatin A is a cysteine proteinase inhibitor that belongs to family 1 of the cystatin superpamily. This gene was assigned to human chromosome 3q21.1. This is an intracellular thiol proteinase inhibitor. Cystatin A plays an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis. Stefins have been proposed as prognostic and diagnostic tools for cancer.

    Sequence Similarities: Belongs to the cystatin family.

    Molekulargewicht
    14 kDa
    Gen-ID
    1475
    UniProt
    P01040
    Pathways
    Response to Water Deprivation
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