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Ectodysplasin A Antikörper (Middle Region)

Der Kaninchen Polyklonal Anti-Ectodysplasin A-Antikörper wurde für WB validiert. Er ist geeignet, Ectodysplasin A in Proben von Human, Maus und Ratte zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN3042668

Kurzübersicht für Ectodysplasin A Antikörper (Middle Region) (ABIN3042668)

Target

Alle Ectodysplasin A (EDA) Antikörper anzeigen
Ectodysplasin A (EDA)

Reaktivität

  • 71
  • 54
  • 28
  • 10
  • 7
  • 7
  • 7
  • 7
  • 6
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 68
  • 6
  • 1
Kaninchen

Klonalität

  • 66
  • 6
  • 2
Polyklonal

Konjugat

  • 28
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Ectodysplasin A Antikörper ist unkonjugiert

Applikation

  • 63
  • 35
  • 26
  • 26
  • 20
  • 12
  • 10
  • 6
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 16
    • 16
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 254-269, Middle Region

    Verwendungszweck

    Anti-Ectodysplasin-A EDA Antibody Picoband®

    Sequenz

    HLQGQGSAIQ VKNDLS

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Ectodysplasin-A EDA Antibody (ABIN3042668). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence in the middle region of human EDA, identical to the related mouse and rat sequences.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Bayes, M., Hartung, A. J., Ezer, S., Pispa, J., Thesleff, I., Srivastava, A. K., Kere, J. The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats. Hum. Molec. Genet. 7: 1661-1669, 1998. 2. Durmowicz, M. C., Cui, C.-Y., Schlessinger, D. The EDA gene is a target of, but does not regulate Wnt signaling. Gene 285: 203-211, 2002.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Ning, Chen, Li, Wu, Wu, Li, Feng: "X-irradiation for inhibiting glial scar formation in injured spinal cord." in: Neural regeneration research, Vol. 8, Issue 17, pp. 1582-9, (2014) (PubMed).

  • Target

    Ectodysplasin A (EDA)

    Andere Bezeichnung

    EDA

    Hintergrund

    Synonyms: Ectodysplasin-A,Ectodermal dysplasia protein,EDA protein,Ectodysplasin-A, membrane form,Ectodysplasin-A, secreted form,EDA,ED1, EDA2,

    Tissue Specificity: Not abundant, expressed in specific cell types of ectodermal (but not mesodermal) origin of keratinocytes, hair follicles, sweat glands. Also in adult heart, liver, muscle, pancreas, prostate, fetal liver, uterus, small intestine and umbilical chord. .

    Background: Anhidrotic ectodermal dysplasia (EDA) is an X-linked recessive disorder which affects ectodermal structures. Ectodysplasin-A, the protein encoded by the EDA gene, is a member of the tumor necrosis factor ligand superfamily that forms a collagen triple helix, suggesting functions in signal transduction and cell adhesion. Wnt signaling does control EDA gene expression, but ectodysplasin-A does not feedback on the Wnt pathway.

    Sequence Similarities: Belongs to the tumor necrosis factor family.

    Molekulargewicht

    60 kDa

    UniProt

    Q92838

    Pathways

    Tube Formation
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