Mip (AA 246-263), (C-Term) Antikörper

Produktnummer ABIN3042655

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Mip in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für Mip (AA 246-263), (C-Term) Antikörper (ABIN3042655)

Target: Mip

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 246-263, C-Term

Verwendungszweck: Anti-Aquaporin 0/MIP Antibody

Sequenz: NGQPEGTGEP VELKTQAL

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Aquaporin 0/MIP Antibody (ABIN3042655). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Aquaporin 0, identical to the related rat sequence, and different from the related human sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Mouse, Human, Rat

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen

Liu, An, Liu, Li, Tang, Chen: "Mouse lung slices: An ex vivo model for the evaluation of antiviral and anti-inflammatory agents against influenza viruses." in: Antiviral research, Vol. 120, pp. 101-11, (2015) (PubMed).

Sun, Zhao, Yao, Zhao, Wu, Wang, Pan, Miao, Guo, Lu: "Wogonoside protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-?B and NLRP3 inflammasome activation." in: Biochemical pharmacology, Vol. 94, Issue 2, pp. 142-54, (2015) (PubMed).

Bruns, Cadeddu, Brueckmann, Fröbel, Geyh, Büst, Fischer, Roels, Wilk, Schildberg, Hünerlitürkoglu, Zilkens, Jäger, Steidl, Zohren, Fenk, Kobbe, Brors, Czibere, Schroeder, Trumpp, Haas: "Multiple myeloma-related deregulation of bone marrow-derived CD34(+) hematopoietic stem and progenitor cells." in: Blood, Vol. 120, Issue 13, pp. 2620-30, (2012) (PubMed).

Antigendetails

Target: Mip

Hintergrund:

Synonyms: Lens fiber major intrinsic protein,Aquaporin-0,MIP26,MP26,Mip,

Tissue Specificity: Major component of lens fiber gap junctions.

Background: Lens fiber major intrinsic protein also called MIP26 or MP26 is a protein that in humans is encoded by the MIP gene. MIP is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. Using 2-color fluorescence in situ hybridization on high-resolution R-banded chromosomes and human genomic DNA clones for MIP as probes, this gene was found that located in close proximity in region 12q13. MIP plays a crucial role in the development of a transparent eye lens. This gene may be responsible for regulating the osmolarity of the lens and interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.

Molekulargewicht: 50 kDa

UniProt: P09011