L-Selectin Antikörper (Middle Region)

Produktnummer ABIN3042616

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch L-Selectin in WB. Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für L-Selectin Antikörper (Middle Region) (ABIN3042616)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser L-Selectin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-L-Selectin Antikörper

Bindungsspezifität: AA 125-141, Middle Region

Verwendungszweck: Anti-CD62L/SELL Antibody Picoband®

Sequenz: KEDCVEIYIK RERDSGK

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-CD62L/SELL Antibody (ABIN3042616). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse L-selectin, identical to the related rat sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Mouse, Rat
1. "Entrez Gene: SELL selectin L (lymphocyte adhesion molecule 1)". 2. Cotran, Kumar, Collins (1998). Robbins Pathologic Basis of Disease. Philadelphia: W.B Saunders Company.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Andere Bezeichnung: SELL

Hintergrund:

Synonyms: L-selectin,CD62 antigen-like family member L,Leukocyte adhesion molecule 1,LAM-1,Leukocyte-endothelial cell adhesion molecule 1,LECAM1,Lymph node homing receptor,Lymphocyte antigen 22,Ly-22,Lymphocyte surface MEL-14 antigen,CD62L,Sell,Lnhr, Ly-22, Ly22,

Tissue Specificity: Predominantly expressed in lymphoid tissue. .

Background: L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin)is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.

Sequence Similarities: Belongs to the selectin/LECAM family.

Molekulargewicht: 70 kDa

UniProt: P18337