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LTA Antikörper (Middle Region)

Dieses Anti-LTA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LTA in WB. Geeignet für Human.
Produktnummer ABIN3042614

Kurzübersicht für LTA Antikörper (Middle Region) (ABIN3042614)

Target

Alle LTA Antikörper anzeigen
LTA (Lymphotoxin-alpha (LTA))

Reaktivität

  • 73
  • 31
  • 12
  • 9
  • 7
  • 7
  • 5
  • 2
  • 2
  • 1
Human

Wirt

  • 86
  • 38
  • 4
  • 1
  • 1
Kaninchen

Klonalität

  • 86
  • 43
  • 1
Polyklonal

Konjugat

  • 83
  • 14
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser LTA Antikörper ist unkonjugiert

Applikation

  • 94
  • 56
  • 40
  • 38
  • 35
  • 11
  • 10
  • 8
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 73-88, Middle Region

    Verwendungszweck

    Anti-TNF beta/LTA Antibody Picoband®

    Sequenz

    KQNSLLWRAN TDRAFL

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-TNF beta/LTA Antibody (ABIN3042614). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence in the middle region of human TNF beta, different from the related mouse sequence by one amino acid.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human
    1. Parham, Peter (2005). "Chapter 6: T-cell mediated immunity". The immune system (2nd ed.). New York: Garland Science. p. 172.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    LTA (Lymphotoxin-alpha (LTA))

    Andere Bezeichnung

    LTA

    Substanzklasse

    Chemical

    Hintergrund

    Synonyms: Lymphotoxin-alpha,LT-alpha,TNF-beta,Tumor necrosis factor ligand superfamily member 1,LTA,TNFB, TNFSF1,

    Tissue Specificity: Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines. .

    Background: Lymphotoxin (previously known as tumor necrosis factor-beta) is a lymphokine cytokine. It is a protein that is produced by Th1 type T-cells and induces vascular endothelial cells to change their surface adhesion molecules to allow phagocytic cells to bind to them. Lymphotoxin is homologous to Tumor Necrosis Factor beta, but secreted by T-cells. It is paracrine due to the small amounts produced. The effects are similar to TNF-alpha, but TNF-beta is also important for the development of lymphoid organs. Nedwin et al. (1985) found that TNFA and TNFB are closely linked on chromosome 6. Study of hybrid cells made with rearranged human chromosome 6 showed that both TNFA and TNFB map to the 6p23-q12 segment.

    Sequence Similarities: Belongs to the tumor necrosis factor family.

    Molekulargewicht

    6 kDa

    UniProt

    P01374

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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