AVPR1A Antikörper (Middle Region)

Produktnummer ABIN3042582

Dieses Anti-AVPR1A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von AVPR1A in WB. Geeignet für Human, Ratte und Maus.

Kurzübersicht für AVPR1A Antikörper (Middle Region) (ABIN3042582)

Target: AVPR1A (Arginine Vasopressin Receptor 1A (AVPR1A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AVPR1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AVPR1A Antikörper

Bindungsspezifität: AA 155-173, Middle Region

Verwendungszweck: Anti-Vasopressin V1a receptor AVPR1A Antibody Picoband®

Sequenz: HPLKTLQQPA RRSRLMIAT

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Vasopressin V1a receptor AVPR1A Antibody (ABIN3042582). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of rat AVPR1A, different from the related human and mouse sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Birnbaumer, M. Vasopressin receptors. Trends Endocr. Metab. 11: 406-410, 2000. 2. Caldwell HK, Lee HJ, Macbeth AH, Young WS (2008). "Vasopressin: behavioral roles of an 'original' neuropeptide". Prog Neurobiol 84 (1): 1-24.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu AVPR1A

Target: AVPR1A (Arginine Vasopressin Receptor 1A (AVPR1A))

Andere Bezeichnung: AVPR1A

Hintergrund:

Synonyms: Vasopressin V1a receptor;V1aR;AVPR V1a;Antidiuretic hormone receptor 1a;Vascular/hepatic-type arginine vasopressin receptor;Avpr1a;

Tissue Specificity: Localized within gonadotropes of the anterior pituitary of the brain. Broadly distributed throughout the cerebral cortex. .

Background: Arginine vasopressin receptor 1A (officially called AVPR1A) is one of the three major receptor types for arginine vasopressin  (AVPR1B and AVPR2 being the others). It belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. This gene is mapped to 12q14.2. AVPR1A is present throughout the brain, as well as in the periphery, in the liver, kidney, and vasculature. The protein encoded by this gene acts as receptor for arginine vasopressin. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.

Sequence Similarities: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Molekulargewicht: 47 kDa

UniProt: P30560

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Response to Water Deprivation, Regulation of Carbohydrate Metabolic Process