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EPB41L1 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-EPB41L1-Antikörper wurde für WB validiert. Er ist geeignet, EPB41L1 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN3042566

Kurzübersicht für EPB41L1 Antikörper (C-Term) (ABIN3042566)

Target

Alle EPB41L1 Antikörper anzeigen
EPB41L1 (erythrocyte Membrane Protein Band 4.1-Like 1 (EPB41L1))

Reaktivität

  • 12
  • 4
  • 4
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 7
  • 5
Kaninchen

Klonalität

  • 10
  • 2
Polyklonal

Konjugat

  • 12
Dieser EPB41L1 Antikörper ist unkonjugiert

Applikation

  • 12
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 585-604, C-Term

    Verwendungszweck

    Anti-Band 4.1-like protein 1 EPB41L1 Antibody Picoband®

    Sequenz

    QDQERDTVFL KDNHLAIERK

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Band 4.1-like protein 1 EPB41L1 Antibody (ABIN3042566). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human EPB41L1, different from the related mouse and rat sequences by one amino acid.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
    1. Binda, Alicia V, Kabbani Nadine, Lin Ridwan, Levenson Robert (September 2002). "D2 and D3 dopamine receptor cell surface localization mediated by interaction with protein 4.1N". Mol. Pharmacol. (United States) 62 (3): 507-13. 2. Hamdan, F. F., Gauthier, J., Araki, Y., Lin, D.-T., Yoshizawa, Y., Higashi, K., Park, A.-R., Spiegelman, D., Dobrzeniecka, S., Piton, A., Tomitori, H., Daoud, H., and 22 others. Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability. Am. J. Hum. Genet. 88: 306-316, 2011. Note: Erratum: Am. J. Hum. Genet. 88: 516 only, 2011. 3. Kim AC, Van Huffel C, Lutchman M, Chishti AH (June 1998). "Radiation hybrid mapping of EPB41L1, a novel protein 4.1 homologue, to human chromosome 20q11.2-q12". Genomics 49 (1): 165-6.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    EPB41L1 (erythrocyte Membrane Protein Band 4.1-Like 1 (EPB41L1))

    Andere Bezeichnung

    EPB41L1

    Hintergrund

    Synonyms: Band 4.1-like protein 1,Neuronal protein 4.1,4.1N,EPB41L1,KIAA0338,

    Tissue Specificity: Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle.

    Background: Band 4.1-like protein 1 is a protein that in humans is encoded by the EPB41L1 gene. This gene is mapped to 20q11.23. It is found that a heterozygous missense mutation in the EPB41L1 gene causing nonsyndromic intellectual disability. This gene may function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. EPB41L1 has been shown to interact with ITPR1, Dopamine receptor D2, Dopamine receptor D3, CENTG1 and Nuclear mitotic apparatus protein 1.

    Sequence Similarities: Contains 1 FERM domain.

    Molekulargewicht

    99 kDa

    UniProt

    Q9H4G0
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