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CCL18 Antikörper (AA 21-89)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CCL18 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN3042511

Kurzübersicht für CCL18 Antikörper (AA 21-89) (ABIN3042511)

Target

Alle CCL18 Antikörper anzeigen
CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))

Reaktivität

  • 30
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 25
  • 5
Kaninchen

Klonalität

  • 25
  • 5
Polyklonal

Konjugat

  • 15
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CCL18 Antikörper ist unkonjugiert

Applikation

  • 22
  • 10
  • 8
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 7
    • 2
    • 1
    • 1
    • 1
    AA 21-89

    Verwendungszweck

    Anti-Macrophage Inflammatory Protein 4/CCL18 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Macrophage Inflammatory Protein 4/CCL18 Antibody Picoband® (ABIN3042511). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human CCL18 recombinant protein (Position: A21-A89).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, -
    ELISA(Cap) , 1-5 μg/mL, Human
    1. Hieshima k, I. T. (August 1997). "A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes". Journal of Immunology 159 (3): 1140-1149. 2. Tasaki, Y., Fukuda, S., Iio, M., Miura, R., Imai, T., Sugano, S., Yoshie, O., Hughes, A. et al. (1999). "Chemokine PARC Gene (SCYA18) Generated by Fusion of Two MIP-1α/LD78α-like Genes, ,". Genomics 55 (3): 353-357. 3. Hieshima, K., Imai, T., Baba, M., Shoudai, K., Ishizuka, K., Nakagawa, T., Tsuruta, J., Takeya, M., Sakaki, Y., Takatsuki, K., Miura, R., Opdenakker, G., Van Damme, J., Yoshie, O., Nomiyama, H. A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1-alpha/LD78-alpha and chemotactic for T lymphocytes, but not for monocytes. J. Immun. 159: 1140-1149, 1997.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))

    Andere Bezeichnung

    CCL18

    Hintergrund

    Synonyms: C-C motif chemokine 18,Alternative macrophage activation-associated CC chemokine 1,AMAC-1,CC chemokine PARC,Dendritic cell chemokine 1,DC-CK1,Macrophage inflammatory protein 4,MIP-4,Pulmonary and activation-regulated chemokine,Small-inducible cytokine A18,CCL18 (1-68),CCL18 (3-69),CCL18 (4-69),CCL18,AMAC1, DCCK1, MIP4, PARC, SCYA18,

    Tissue Specificity: Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid. .

    Background: Macrophage Inflammatory Protein 4, also known as CCL18, is a small cytokine belonging to the CC chemokine family that was previously called PARC (pulmonary and activation-regulated chemokine). CCL18 is approximately 60 % identical in amino acid sequence to CCL3. By analysis of a previously mapped CCL18 from 17q11.2, it is determined that the PARC gene is located within 1 of the 2 clusters of CC chemokine genes in this region. It is expressed at high levels in lung and at lower levels in certain lymphoid tissues, such as the lymph nodes, and is chemotactic for activated T cells and nonactivated lymphocytes. Beside, CCL18 recruits Th2 cells and basophils and may play a predominant role in allergic asthma.

    Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

    Molekulargewicht

    19 kDa

    Gen-ID

    6362

    UniProt

    P55774
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