Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

LOXL1 Antikörper (C-Term)

Dieses Anti-LOXL1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LOXL1 in WB und IHC. Geeignet für Human.
Produktnummer ABIN3042507

Kurzübersicht für LOXL1 Antikörper (C-Term) (ABIN3042507)

Target

Alle LOXL1 Antikörper anzeigen
LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Reaktivität

  • 55
  • 22
  • 9
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Human

Wirt

  • 59
  • 7
Kaninchen

Klonalität

  • 61
  • 5
Polyklonal

Konjugat

  • 35
  • 11
  • 10
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LOXL1 Antikörper ist unkonjugiert

Applikation

  • 45
  • 25
  • 19
  • 18
  • 15
  • 9
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 10
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 397-425, C-Term

    Verwendungszweck

    Anti-LOXL1 Antibody Picoband®

    Sequenz

    AEEKCLASTA YAPEATDYDV RVLLRFPQR

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-LOXL1 Antibody Picoband® (ABIN3042507). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL1, different from the related mouse sequence by one amino acid.

    Isotyp

    IgG
  • Applikationshinweise

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. Kenyon K, Modi WS, Contente S, Friedman RM (September 1993). "A novel human cDNA with a predicted protein similar to lysyl oxidase maps to chromosome 15q24-q25". The Journal of Biological Chemistry 268 (25): 18435-7. 2. Liu X, Zhao Y, Gao J, Pawlyk B, Starcher B, Spencer JA, Yanagisawa H, Zuo J, Li T (Feb 2004). "Elastic fiber homeostasis requires lysyl oxidase-like 1 protein". Nat. Genet. (United States) 36 (2): 178-82. 3. "Entrez Gene: LOXL1 lysyl oxidase-like 1".

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

    Andere Bezeichnung

    LOXL1

    Hintergrund

    Synonyms: Lysyl oxidase homolog 1,1.4.3.-,Lysyl oxidase-like protein 1,LOL,LOXL1,LOXL,

    Tissue Specificity: Expressed in ocular tissues including the iris, ciliary body, lens and optic nerve. Not detected in the retina. .

    Background: Lysyl oxidase homolog 1, also known as?LOXL1, is an?enzyme?which in humans is encoded by the?LOXL1?gene. This gene encodes a member of the?lysyl oxidase?gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in?collagens?and?elastin. A highly conserved amino acid sequence at the C-terminus?end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The?N-terminus?is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and?chemotaxis?to each member of the family.

    Molekulargewicht

    63 kDa

    Gen-ID

    4016

    UniProt

    Q08397
Sie sind hier:
Chat with us!