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SP5 Antikörper (Middle Region)

SP5 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042490
  • Target Alle SP5 Antikörper anzeigen
    SP5 (Sp5 Transcription Factor (SP5))
    Bindungsspezifität
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 246-275, Middle Region
    Reaktivität
    • 6
    • 5
    Human
    Wirt
    • 6
    Kaninchen
    Klonalität
    • 6
    Polyklonal
    Konjugat
    • 6
    Dieser SP5 Antikörper ist unkonjugiert
    Applikation
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    Anti-Sp5 Antibody Picoband®
    Sequenz
    DFAQYQSQIA ALLQTKAPLA ATARRCRRCR
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-Sp5 Antibody Picoband® (ABIN3042490). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human Sp5, identical to the related mouse sequence.
    Isotyp
    IgG
    Top Product
    Discover our top product SP5 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. Chen Y, Guo Y, Ge X, Itoh H, Watanabe A, Fujiwara T, Kodama T, Aburatani H: Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers. Biochem Biophys Res Commun, 2006 Feb 17. 2. Simmons SO, Horowitz JM: Nkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cells. Biochem J, 2006 Jan 1.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    SP5 (Sp5 Transcription Factor (SP5))
    Andere Bezeichnung
    SP5 (SP5 Produkte)
    Hintergrund

    Synonyms: Transcription factor Sp5,SP5,

    Tissue Specificity: Expressed in brain and lymphoblasts. .

    Background: Sp5 is mapped to 2q31.1. It is a member of the Sp family of zinc finger transcription factors. Like other family members, the Sp5 protein contains a Cys2His2 zinc finger DNA binding domain at the C-terminus. Elevated expression of Sp5 has been noted in several human tumors including hepatocellular carcinoma, gastric cancer and colon cancer.

    Sequence Similarities: Belongs to the Sp1 C2H2-type zinc-finger protein family.

    Molekulargewicht
    42 kDa
    Gen-ID
    389058
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