KAT2A Antikörper (N-Term)

Produktnummer ABIN3042472

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch KAT2A in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KAT2A Antikörper (N-Term) (ABIN3042472)

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KAT2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KAT2A Antikörper

Bindungsspezifität: AA 75-106, N-Term

Verwendungszweck: Anti-KAT2A/GCN5 Antibody

Sequenz: DPARPGLSQQ QRASQRKAQV RGLPRAKKLE KL

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-KAT2A/GCN5 Antibody (ABIN3042472). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human KAT2A/GCN5, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu KAT2A

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Andere Bezeichnung: KAT2A

Hintergrund:

Synonyms: Histone acetyltransferase KAT2A,2.3.1.48,General control of amino acid synthesis protein 5-like 2,Histone acetyltransferase GCN5,HsGCN5,Lysine acetyltransferase 2A,STAF97,KAT2A,GCN5, GCN5L2, HGCN5,

Tissue Specificity: Expressed in all tissues tested, with most abundant expression in ovary.

Background: Histone acetyltransferase KAT2A?is an?enzyme?that in humans is encoded by the?KAT2A?gene. It is mapped to 17q21. KAT2A, or GCN5, GCN5L2, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. The GCN5 protein, a regulator of transcription activation in yeast, promotes maximal levels of transcription by 2 transcriptional activators, GCN4 and the HAP2-HAP3-HAP4 complex.?The GCN4 protein activates transcription of a large number of amino acid biosynthetic genes under limiting amino acid conditions and the HAP2-HAP3-HAP4 complex is thought to mediate transcription of genes involved in respiratory functions.?GCN5 also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner.

Molekulargewicht: 94 kDa

Gen-ID: 2648

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation