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HRG Antikörper (AA 19-200)

HRG Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042459
  • Target Alle HRG Antikörper anzeigen
    HRG (Histidine-Rich Glycoprotein (HRG))
    Bindungsspezifität
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 19-200
    Reaktivität
    • 27
    • 7
    • 3
    • 1
    Human
    Wirt
    • 29
    • 5
    • 1
    Kaninchen
    Klonalität
    • 31
    • 4
    Polyklonal
    Konjugat
    • 20
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HRG Antikörper ist unkonjugiert
    Applikation
    • 25
    • 11
    • 8
    • 6
    • 6
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    Anti-HRG Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-HRG Antibody Picoband® (ABIN3042459). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human HRG recombinant protein (Position: V19-V200). Human HRG shares 71% and 69% amino acid (aa) sequences identity with mouse and rat HRG, respectively.
    Isotyp
    IgG
    Top Product
    Discover our top product HRG Primärantikörper
  • Applikationshinweise
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. Hennis BC, Kluft C (Sep 1991). "KpnI RFLP in the human histidine-rich glycoprotein gene". Nucleic Acids Res 19 (15): 4311-4311. 2. "Entrez Gene: HRG histidine-rich glycoprotein" 3. Poon IK, Patel KK, Davis DS, Parish CR, Hulett MD (2011). "Histidine-rich glycoprotein: the Swiss Army knife of mammalian plasma". Blood 117 (7): 2093-101.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    HRG (Histidine-Rich Glycoprotein (HRG))
    Andere Bezeichnung
    HRG (HRG Produkte)
    Hintergrund

    Synonyms: Histidine-rich glycoprotein,Histidine-proline-rich glycoprotein,HPRG,HRG,

    Tissue Specificity: Expressed in macrophages and in malignant cells. Expressed by the liver and secreted in plasma (at protein level). .

    Background: Histidine-rich glycoprotein (HRG) is a protein that in humans is encoded by the HRG gene. It is mapped to 3q27.3. HRG contains two cystatin-like domains and is located in plasma and platelets. The protein can bind heme, dyes and divalent metal ions. It also can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. HRG is thought to have multiple roles as a protein in the human blood, including roles in immunity, angiogenesis and coagulation.

    Molekulargewicht
    60 kDa
    Gen-ID
    3273
    UniProt
    P04196
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