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HMOX2 Antikörper (AA 2-316)

Dieses Anti-HMOX2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HMOX2 in WB und IHC. Geeignet für Human.
Produktnummer ABIN3042450

Kurzübersicht für HMOX2 Antikörper (AA 2-316) (ABIN3042450)

Target

Alle HMOX2 Antikörper anzeigen
HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Reaktivität

  • 74
  • 28
  • 27
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 69
  • 9
  • 1
  • 1
Kaninchen

Klonalität

  • 72
  • 8
Polyklonal

Konjugat

  • 38
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HMOX2 Antikörper ist unkonjugiert

Applikation

  • 56
  • 25
  • 24
  • 24
  • 14
  • 13
  • 13
  • 13
  • 10
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 16
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-316

    Verwendungszweck

    Anti-Heme oxygenase 2/HMOX2 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Heme oxygenase 2/HMOX2 Antibody Picoband® (ABIN3042450). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human HMOX2 recombinant protein (Position: S2-M316). Human HMOX2 shares 89% and 90% amino acid (aa) sequences identity with mouse and rat HMOX2, respectively.

    Isotyp

    IgG
  • Applikationshinweise

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. McCoubrey WK Jr, Ewing JF, Maines MD (Jun 1992). "Human heme oxygenase-2: characterization and expression of a full-length cDNA and evidence suggesting that the two HO-2 transcripts may differ by choice of polyadenylation signal". Arch Biochem Biophys 295 (1): 13-20. 2. "Entrez Gene: HMOX2 heme oxygenase (decycling) 2"

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

    Andere Bezeichnung

    HMOX2

    Hintergrund

    Synonyms: Heme oxygenase 2,HO-2,1.14.99.3,HMOX2,HO2,

    Background: Heme oxygenase 2 (HMOX2), also known as HO-2, is an enzyme that in humans is encoded by the HMOX2 gene. It is mapped to 16p13.3. HMOX2 belongs to the heme oxygenase family. Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

    Sequence Similarities: Belongs to the heme oxygenase family.

    Molekulargewicht

    38 kDa

    Gen-ID

    3163

    UniProt

    P30519

    Pathways

    Transition Metal Ion Homeostasis
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