GATA5 Antikörper (AA 1-397)

Produktnummer ABIN3042418

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GATA5 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GATA5 Antikörper (AA 1-397) (ABIN3042418)

Target: GATA5 (GATA Binding Protein 5 (GATA5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GATA5 Antikörper

Bindungsspezifität: AA 1-397

Verwendungszweck: Anti-GATA5 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-GATA5 Antibody Picoband® (ABIN3042418). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GATA5 recombinant protein (Position: M1-A397). Human GATA5 shares 75% amino acid (aa) sequence identity with mouse GATA5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human
1. Gao, X., Sedgwick, T., Shi, Y.-B., Evans, T. Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation. Molec. Cell. Biol. 18: 2901-2911, 1998. 2. "Entrez Gene: GATA5 GATA binding protein 5"

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu GATA5

Target: GATA5 (GATA Binding Protein 5 (GATA5))

Andere Bezeichnung: GATA5

Hintergrund:

Synonyms: Transcription factor GATA-5,GATA-binding factor 5,GATA5 ,

Tissue Specificity: T-cells and endothelial cells.

Background: Transcription factor GATA-5, also named GATAS or GATA5, is a protein that in humans is encoded by the GATA5 gene. It is mapped to 20q13.33. The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. In addition, the expression of GATA5 increased in a human colon cancer cell line within 2 hours of exposure to sodium butyrate, which induces differentiation.

Sequence Similarities: Contains 2 GATA-type zinc fingers.

Molekulargewicht: 50 kDa

Gen-ID: 140628