Glucose-6-Phosphate Dehydrogenase Antikörper (AA 315-515)

Produktnummer ABIN3042413

Produktdetails anti-Glucose-6-Phosphate Dehydrogenase Antikörper

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Bindungsspezifität: AA 315-515

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glucose-6-Phosphate Dehydrogenase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Glucose-6-phosphate 1-dehydrogenase(G6PD) detection. Tested with WB in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Glucose-6-phosphate 1-dehydrogenase(G6PD) detection. Tested with WB in Human.
Gene Name: glucose-6-phosphate dehydrogenase
Protein Name: Glucose-6-phosphate 1-dehydrogenase

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human G6PD recombinant protein (Position: E315-L515). Human G6PD shares 95% and 96% amino acid (aa) sequences identity with mouse and rat G6PD, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for G6PD is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-Glucose-6-Phosphate Dehydrogenase Antikörper (ABIN3042413)

Hu, Zhang, Tang, Su, Li, Chen, Zhang, Cai, Zhu: "Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model." in: BMC cancer, Vol. 13, Issue 1, pp. 251, (2014) (PubMed).

Details zu Glucose-6-Phosphate Dehydrogenase

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Andere Bezeichnung: G6PD (G6PD Produkte)

Synonyme: G6PD1 antikoerper, g6pd antikoerper, G6pd antikoerper, G6pdx antikoerper, g6pdh antikoerper, g6pd2 antikoerper, fj78b06 antikoerper, wu:fj78b06 antikoerper, si:dkey-90a13.8 antikoerper, BA3433 antikoerper, CORTRD1 antikoerper, G6PDH antikoerper, GDH antikoerper, G28A antikoerper, G6PD antikoerper, Gpdx antikoerper, glucose-6-phosphate dehydrogenase antikoerper, glucose-6-phosphate 1-dehydrogenase antikoerper, glucose-6-phosphate 1-dehydrogenase (G6PD) antikoerper, glucose-6-P dehydrogenase antikoerper, glucose-6-phosphate dehydrogenase L homeolog antikoerper, glucose-6-phosphate 1-dehydrogenase Zwf antikoerper, hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase antikoerper, glucose-6-phosphate dehydrogenase X-linked antikoerper, G6PD antikoerper, g6pd antikoerper, g6pD antikoerper, zwf antikoerper, LOC100120232 antikoerper, LACBIDRAFT_188936 antikoerper, G6pd antikoerper, g6pd.L antikoerper, CNG03280 antikoerper, Tb10.70.5200 antikoerper, H6PD antikoerper, G6pdx antikoerper, H6pd antikoerper

Hintergrund: Glucose-6-phosphate dehydrogenase, also known as G6PD or G6PDH, is an enzyme that in humans is encoded by the G6PD gene. It is mapped to Xq28. G6PD plays a key role in the production of ribose 5-phosphate and the generation of NADPH in the hexose monophosphate pathway. Because this pathway is the only NADPH-generation process in mature red cells, which lack the citric adid cycle, a genetic deficiency of G6PD is often associated with adverse physiologic effects. It has been found that aldosterone decreased G6PD expression and activity, resulting in increased oxidant stress and decreased nitric oxide levels, similar to what is observed in G6PD-deficient endothelial cells.

Synonyms: G6PD antibody|G6PD_HUMAN antibody|G6PD1 antibody|G6pdx antibody|Glucose 6 phosphate 1 dehydrogenase antibody|Glucose 6 phosphate dehydrogenase antibody|Glucose 6 phosphate dehydrogenase, G6PD antibody|Glucose-6-phosphate 1-dehydrogenase antibody|MET19 antibody|POS10 antibody|Zwf1p antibody

Gen-ID: 2539

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones