FMO2 Antikörper (N-Term)
Kurzübersicht für FMO2 Antikörper (N-Term) (ABIN3042397)
Target
Alle FMO2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- AA 78-115, N-Term
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                                            Verwendungszweck
- Anti-FMO2 Antibody Picoband®
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                                            Sequenz
- FPNFLHNSKL LEYFRIFAKK FDLLKYIQFQ TTVLSVRK
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                                            Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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                                            Produktmerkmale
- Anti-FMO2 Antibody Picoband® (ABIN3042397). Tested in WB applications. This antibody reacts with Human;Mouse;Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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                                            Aufreinigung
- Immunogen affinity purified.
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                                            Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human FMO2, different from the related mouse and rat sequences by two amino acids.
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                                            Isotyp
- IgG
 
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                                            Applikationshinweise
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                        Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
 1. "Entrez Gene: FMO2 flavin containing monooxygenase 2 (non-functional)". 2. Dolphin CT, Shephard EA, Povey S, Smith RL, Phillips IR (Nov 1992). "Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family".Biochem J. 287. ( Pt 1): 261-7. 3. Dolphin CT, Beckett DJ, Janmohamed A, Cullingford TE, Smith RL, Shephard EA, Phillips IR (Dec 1998). "The flavin-containing monooxygenase 2 gene (FMO2) of humans, but not of other primates, encodes a truncated, nonfunctional protein". J Biol Chem 273 (46): 30599-607.
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                                            Kommentare
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                        Antibody can be supported by chemiluminescence kit ABIN921124 in WB. 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Lyophilized
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                                            Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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                                            Konzentration
- 500 μg/mL
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                                            Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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                                            Handhabung
- Avoid repeated freezing and thawing.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
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                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
 
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    - FMO2 (Flavin Containing Monooxygenase 2 (Non-Functional) (FMO2))
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                                            Andere Bezeichnung
- FMO2
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                                            Hintergrund
- 
                        Synonyms: Dimethylaniline monooxygenase [N-oxide-forming] 2,1.14.13.8,Dimethylaniline oxidase 2,FMO 1B1,Pulmonary flavin-containing monooxygenase 2,FMO 2,FMO2, Tissue Specificity: Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain. . Background: Dimethylaniline monooxygenase [N-oxide-forming] 2 is an enzyme that in humans is encoded by the FMO2 gene. This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. 
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                                            Molekulargewicht
- 61 kDa
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                                            Gen-ID
- 2327
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                                            UniProt
- Q99518
 Target
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