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FMO2 Antikörper (N-Term)

This anti-FMO2 antibody (ABIN3042397) is a Rabbit Polyclonal antibody detecting FMO2 in WB. Suitable for Human, Rat, Mouse.
Produktnummer ABIN3042397

Quick Overview for FMO2 Antikörper (N-Term) (ABIN3042397)

Target

Alle FMO2 Antikörper anzeigen
FMO2 (Flavin Containing Monooxygenase 2 (Non-Functional) (FMO2))

Reaktivität

  • 11
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Ratte, Maus

Wirt

  • 16
Kaninchen

Klonalität

  • 16
Polyklonal

Konjugat

  • 16
Dieser FMO2 Antikörper ist unkonjugiert

Applikation

  • 15
  • 10
  • 6
  • 6
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 78-115, N-Term

    Verwendungszweck

    Anti-FMO2 Antibody Picoband®

    Sequenz

    FPNFLHNSKL LEYFRIFAKK FDLLKYIQFQ TTVLSVRK

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-FMO2 Antibody Picoband® (ABIN3042397). Tested in WB applications. This antibody reacts with Human;Mouse;Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the N-terminus of human FMO2, different from the related mouse and rat sequences by two amino acids.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene: FMO2 flavin containing monooxygenase 2 (non-functional)". 2. Dolphin CT, Shephard EA, Povey S, Smith RL, Phillips IR (Nov 1992). "Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family".Biochem J. 287. ( Pt 1): 261-7. 3. Dolphin CT, Beckett DJ, Janmohamed A, Cullingford TE, Smith RL, Shephard EA, Phillips IR (Dec 1998). "The flavin-containing monooxygenase 2 gene (FMO2) of humans, but not of other primates, encodes a truncated, nonfunctional protein". J Biol Chem 273 (46): 30599-607.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    FMO2 (Flavin Containing Monooxygenase 2 (Non-Functional) (FMO2))

    Andere Bezeichnung

    FMO2

    Hintergrund

    Synonyms: Dimethylaniline monooxygenase [N-oxide-forming] 2,1.14.13.8,Dimethylaniline oxidase 2,FMO 1B1,Pulmonary flavin-containing monooxygenase 2,FMO 2,FMO2,

    Tissue Specificity: Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain. .

    Background: Dimethylaniline monooxygenase [N-oxide-forming] 2 is an enzyme that in humans is encoded by the FMO2 gene. This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants.

    Molekulargewicht

    61 kDa

    Gen-ID

    2327

    UniProt

    Q99518
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