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EPB41L1 Antikörper (AA 691-881)

EPB41L1 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042373
  • Target Alle EPB41L1 Antikörper anzeigen
    EPB41L1 (erythrocyte Membrane Protein Band 4.1-Like 1 (EPB41L1))
    Bindungsspezifität
    • 4
    • 2
    • 2
    • 2
    • 1
    AA 691-881
    Reaktivität
    • 12
    • 4
    • 4
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 7
    • 5
    Kaninchen
    Klonalität
    • 10
    • 2
    Polyklonal
    Konjugat
    • 12
    Dieser EPB41L1 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Anti-EPB41L1 Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-EPB41L1 Antibody Picoband® (ABIN3042373). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human EPB41L1 recombinant protein (Position: Q691-S881). Human EPB41L1 shares 91% amino acid (aa) sequence identity with both mouse and rat EPB41L1.
    Isotyp
    IgG
    Top Product
    Discover our top product EPB41L1 Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Binda, Alicia V, Kabbani Nadine, Lin Ridwan, Levenson Robert (September 2002). "D2 and D3 dopamine receptor cell surface localization mediated by interaction with protein 4.1N". Mol. Pharmacol. (United States) 62 (3): 507-13. 2. Hamdan, F. F., Gauthier, J., Araki, Y., Lin, D.-T., Yoshizawa, Y., Higashi, K., Park, A.-R., Spiegelman, D., Dobrzeniecka, S., Piton, A., Tomitori, H., Daoud, H., and 22 others. Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability. Am. J. Hum. Genet. 88: 306-316, 2011. Note: Erratum: Am. J. Hum. Genet. 88: 516 only, 2011. 3. Kim AC, Van Huffel C, Lutchman M, Chishti AH (June 1998). "Radiation hybrid mapping of EPB41L1, a novel protein 4.1 homologue, to human chromosome 20q11.2-q12". Genomics 49 (1): 165-6.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    EPB41L1 (erythrocyte Membrane Protein Band 4.1-Like 1 (EPB41L1))
    Andere Bezeichnung
    EPB41L1 (EPB41L1 Produkte)
    Hintergrund

    Synonyms: Band 4.1-like protein 1,Neuronal protein 4.1,4.1N,EPB41L1,KIAA0338,

    Tissue Specificity: Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle.

    Background: Band 4.1-like protein 1 is a protein that in humans is encoded by the EPB41L1 gene. This gene is mapped to 20q11.23. It is found that a heterozygous missense mutation in the EPB41L1 gene causing nonsyndromic intellectual disability. This gene may function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. What's more, EPB41L1 is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane.

    Sequence Similarities: Contains 1 FERM domain.

    Molekulargewicht
    98 kDa
    Gen-ID
    2036
    UniProt
    Q9H4G0
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