MGST1 Antikörper (N-Term)

Produktnummer ABIN3042364

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MGST1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für MGST1 Antikörper (N-Term) (ABIN3042364)

Target: MGST1 (Microsomal Glutathione S-Transferase 1 (MGST1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MGST1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MGST1 Antikörper

Bindungsspezifität: AA 42-75, N-Term

Verwendungszweck: Anti-Microsomal Glutathione S-transferase 1/MGST1 Antibody Picoband®

Sequenz: KVFANPEDCV AFGKGENAKK YLRTDDRVER VRRA

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Microsomal Glutathione S-transferase 1/MGST1 Antibody Picoband® (ABIN3042364). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MGST1, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human1. Lee SH, DeJong J (1999). "Microsomal GST-I: genomic organization, expression, and alternative splicing of the human gene.". Biochim. Biophys. Acta 1446 (3): 389-96. 2. "Entrez Gene: MGST1 microsomal glutathione S-transferase 1".

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu MGST1

Target: MGST1 (Microsomal Glutathione S-Transferase 1 (MGST1))

Andere Bezeichnung: MGST1

Hintergrund:

Synonyms: Microsomal glutathione S-transferase 1,Microsomal GST-1,2.5.1.18,Microsomal GST-I,MGST1,GST12, MGST,

Tissue Specificity: Highly expressed in liver.

Background: Microsomal glutathione S-transferase 1 is an enzyme that in humans is encoded by the MGST1 gene. The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene.

Molekulargewicht: 15 kDa

Gen-ID: 4257

UniProt: P10620