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TTR Antikörper (AA 21-147)

TTR Reaktivität: Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042346
  • Target Alle TTR Antikörper anzeigen
    TTR (Transthyretin (TTR))
    Bindungsspezifität
    • 32
    • 16
    • 8
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-147
    Reaktivität
    • 109
    • 44
    • 33
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 121
    • 23
    • 15
    • 7
    • 2
    • 1
    Kaninchen
    Klonalität
    • 134
    • 35
    Polyklonal
    Konjugat
    • 64
    • 28
    • 25
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TTR Antikörper ist unkonjugiert
    Applikation
    • 104
    • 65
    • 60
    • 26
    • 21
    • 14
    • 12
    • 11
    • 11
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Verwendungszweck
    Anti-Prealbumin/TTR Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-Prealbumin/TTR Antibody Picoband® (ABIN3042346). Tested in IF, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived rat Prealbumin recombinant protein (Position: G21-N147). Rat Prealbumin shares 94.5% amino acid (aa) sequence identity with mouse Prealbumin.
    Isotyp
    IgG
    Top Product
    Discover our top product TTR Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
    Immunofluorescence, 5 μg/mL, Mouse, Rat
    1. Benson, M. D., Dwulet, F. E. Identification of carriers of a variant plasma prealbumin (transthyretin) associated with familial amyloidotic polyneuropathy type I. J. Clin. Invest. 75: 71-75, 1985. 2. Sparkes, R. S., Sasaki, H., Mohandas, T., Yoshioka, K., Klisak, I., Sakaki, Y., Heinzmann, C., Simon, M. I. Assignment of the prealbumin (PALB) gene (familial amyloidotic polyneuropathy) to human chromosome region 18q11.2-q12.1. Hum. Genet. 75: 151-154, 1987.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    TTR (Transthyretin (TTR))
    Andere Bezeichnung
    Ttr (TTR Produkte)
    Hintergrund

    Synonyms: Transthyretin,Prealbumin,TBPA,Ttr,Tt,

    Tissue Specificity: Detected in serum and cerebrospinal fluid (at protein level). Highly expressed in the choroid plexus. Detected at lower levels in the liver. .

    Background: Transthyretin (TTR) is also known as prealbumin. It is mapped to chromosome region 18q11.2-q12.1. This gene encodes a carrier protein responsible for the transport of thyroid hormones and retinol. The protein consists of a tetramer of identical subunits. Due to increased stability of the tetramer form of this encoded protein in mouse, compared to the human protein, this gene product has a reduced tendency to form amyloid fibrils. In humans, this protein binds beta-amyloid preventing its aggregation and providing a neuroprotective role in Alzheimer's disease.

    Molekulargewicht
    16 kDa
    Gen-ID
    24856
    UniProt
    P02767
    Pathways
    Hormone Transport
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