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CD16 Antikörper (Biotin)

CD16 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-154 Biotin

Produktnummer ABIN303523

Datenblatt (PDF)

Target Alle CD16 Antikörper anzeigen

CD16
Reaktivität
149

29

21

21

21

9

9

8

8

4

3

3

2

2

2

2

2

2

2

2

2

2
Human
Wirt
132

26

20

1
Maus
Passende Sekundärantikörper
Klonalität
153

24

1
Monoklonal
Konjugat
67

19

14

14

9

5

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD16 Antikörper ist konjugiert mit Biotin
Applikation
145

36

31

28

27

25

23

20

6

6

6

4

4

3

2

2

2

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

This antibody reacts with the epitope on CD16 antigen that residing in proximity to FG loop (probably BC or C'E loop). CD16 is a low affinity receptor for aggregated IgG (FcgRIII antigen). The antibody reacts with CD16+ granulocytes.

Immunogen

Human granulocytes

Klon

MEM-154

Isotyp

IgG1

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anti-CD16 (CD16) antibody
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anti-CD16 (CD16) antibody
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anti-CD16 (CD16) antibody (Biotin)
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Applikationshinweise

Flow cytometry: starting point for use in indirect immunoflourescence is 1:500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

PBS, pH ~7.4 with 15 mM Sodium Azide as preservative.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit

12 months
Target

CD16

Andere Bezeichnung

CD16 (CD16 Produkte)

Hintergrund

CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A

Gen-ID

2214

UniProt

P08637

Pathways

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process