STRA8 Antikörper (AA 341-355)

Produktnummer ABIN3032753

Produktdetails anti-STRA8 Antikörper

Target: STRA8 (Stimulated By Retinoic Acid 8 (STRA8))

Bindungsspezifität: AA 341-355

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRA8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Amino acids 341-355 (DDDVMLLKCLETFDD-rat) were used as the immunogen for this Stra8 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Stra8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Stra8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu STRA8

Target: STRA8 (Stimulated By Retinoic Acid 8 (STRA8))

Andere Bezeichnung: Stra8 (STRA8 Produkte)

Synonyme: RGD1562852 antikoerper, stimulated by retinoic acid 8 antikoerper, stimulated by retinoic acid gene 8 antikoerper, STRA8 antikoerper, Stra8 antikoerper

Hintergrund: Stimulated by retinoic acid 8 is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons. And this gene is mapped to chromosome 7q31. Retinoic acid (RA) signaling was required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying expression in embryonic testis. Since RA signaling regulated Stra8 expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.

UniProt: D4ADQ4