SIRT3 Antikörper (AA 66-399)

Produktnummer ABIN3032592

Dieses Anti-SIRT3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SIRT3 in WB. Geeignet für Human und Ratte.

Kurzübersicht für SIRT3 Antikörper (AA 66-399) (ABIN3032592)

Target: SIRT3 (Sirtuin 3 (SIRT3))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIRT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SIRT3 Antikörper

Bindungsspezifität: AA 66-399

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 66-399) was used as the immunogen for this SIRT3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the SIRT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the SIRT3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu SIRT3

Target: SIRT3 (Sirtuin 3 (SIRT3))

Andere Bezeichnung: SIRT3

Hintergrund: NAD-dependent deacetylase sirtuin-3, mitochondrial is a protein that in humans is encoded by the SIRT3 gene. It is member of the mammalian sirtuin family of proteins, which are homologs to the yeast Sir2 protein. Endogenous SIRT3 is a soluble protein located in the mitochondrial matrix. Overexpression in cultured cells increases respiration and decreases the production of reactive oxygen species. It can function as a mitochondrial deacetylase. Additionally, human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.

Gen-ID: 23410