Ectodysplasin A2 Receptor Antikörper

Produktnummer ABIN303257

Produktdetails anti-Ectodysplasin A2 Receptor Antikörper

Target: Ectodysplasin A2 Receptor (EDA2R)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ectodysplasin A2 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody reacts to Human EDA2R, antibody does not detect mouse EDA2R.

Aufreinigung: Purified

Immunogen: Recombinant human EDA2R

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Ectodysplasin A2 Receptor

Target: Ectodysplasin A2 Receptor (EDA2R)

Andere Bezeichnung: EDA2R / TNFRSF27 (EDA2R Produkte)

Synonyme: EDA-A2R antikoerper, EDAA2R antikoerper, TNFRSF27 antikoerper, XEDAR antikoerper, 9430060M22Rik antikoerper, Xedar antikoerper, RGD1564025 antikoerper, ectodysplasin A2 receptor antikoerper, EDA2R antikoerper, Eda2r antikoerper

Hintergrund: EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support.Synonyms: EDA-A2 receptor, Tumor necrosis factor receptor superfamily member 27, UNQ2448/PRO5727/PRO34080, X-linked ectodysplasin-A2 receptor, XEDAR

Gen-ID: 60401

NCBI Accession: NP_001186616

UniProt: Q9HAV5