SERPINC1 Antikörper (N-Term)

Produktnummer ABIN3032537

Der Kaninchen Polyklonal Anti-SERPINC1-Antikörper wurde für WB validiert. Er ist geeignet, SERPINC1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SERPINC1 Antikörper (N-Term) (ABIN3032537)

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SERPINC1 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human AT3 (TFYQHLADSKNDNDN) was used as the immunogen for this Antithrombin III antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Antithrombin III antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Antithrombin III antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu SERPINC1

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Andere Bezeichnung: Antithrombin III

Hintergrund: Antithrombin III (AT3), is the most important inhibitor of thrombin and other coagulation proteinases. It is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

UniProt: P01008