RAB3A Antikörper (AA 192-220)

Produktnummer ABIN3032423

Produktdetails anti-RAB3A Antikörper

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Bindungsspezifität: AA 192-220

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Amino acids 192-220 (DTADPAVTGAKQGPQLSDQQVPPHQDCAC-human) were used as the immunogen for this Rab3A antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Rab3A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Rab3A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu RAB3A

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Andere Bezeichnung: Rab3A (RAB3A Produkte)

Synonyme: RAB3 antikoerper, rab3a antikoerper, zgc:92276 antikoerper, RAB3A antikoerper, rab-3a antikoerper, si:ch211-255d18.4 antikoerper, zgc:112516 antikoerper, RAB3A, member RAS oncogene family antikoerper, RAB3A, member RAS oncogene family, a antikoerper, RAB3A, member RAS oncogene family L homeolog antikoerper, RAB3A, member RAS oncogene family, b antikoerper, RAB3A antikoerper, Rab3a antikoerper, rab3aa antikoerper, rab3a.L antikoerper, rab3a antikoerper, rab3ab antikoerper

Hintergrund: Ras-related protein Rab-3A is a protein that in humans is encoded by the RAB3A gene. Synapsin I stimulated the Rab3A cycle by increasing GTP binding, GTPase activity, and Rab3A recruitment to the synaptic vesicle membrane. Conversely, Rab3A inhibited Synapsin I binding to actin and Synapsin I-induced synaptic vesicle clustering. It has been found that the protein is necessary for both forms of synaptic plasticity, and it is also involved in calcium exocytosis in neurons. In addition to that, Rab3A has been found to regulate a late step in synaptic vesicle fusion.

Gen-ID: 5864

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport