Plakophilin 2 Antikörper (C-Term)

Produktnummer ABIN3032241

Dieses Anti-Plakophilin 2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Plakophilin 2 in WB. Geeignet für Human, Ratte und Maus.

Kurzübersicht für Plakophilin 2 Antikörper (C-Term) (ABIN3032241)

Target: Plakophilin 2 (PKP2)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Plakophilin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Plakophilin 2 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human PKP2 (KKTDFVNSRTAKAYHSLKD) was used as the immunogen for this Plakophilin 2 antibody (100% mouse homology).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Plakophilin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Plakophilin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Plakophilin 2

Target: Plakophilin 2 (PKP2)

Andere Bezeichnung: Plakophilin 2

Hintergrund: Plakophilin-2 is a protein that in humans is encoded by the PKP2 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. PKP2 is a constituent of the desmosomal plaque in simple epithelia, some stratified epithelia, and some nonepithelial cells. It is also enriched in the karyoplasm of cells of various types, including those lacking desmosomes. PKP proteins participate in linking cadherins to intermediate filaments in the cytoskeleton and this gene product may regulate the signaling activity of beta-catenin. Plakophilin-2 has been shown to interact with Desmoplakin, Plakoglobin and Desmoglein 1.

UniProt: Q99959

Pathways: Cell-Cell Junction Organization, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion