Peroxiredoxin 3 Antikörper (AA 239-256)

Produktnummer ABIN3032188

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Peroxiredoxin 3 in WB, ICC und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für Peroxiredoxin 3 Antikörper (AA 239-256) (ABIN3032188)

Target: Peroxiredoxin 3 (PRDX3)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peroxiredoxin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Peroxiredoxin 3 Antikörper

Bindungsspezifität: AA 239-256

Aufreinigung: Antigen affinity

Immunogen: Amino acids 239-256 (TIKPSPAASKEYFQKVNQ-human) were used as the immunogen for this Peroxiredoxin 3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Titration of the Peroxiredoxin 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: The lyophilized Peroxiredoxin 3 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Peroxiredoxin 3

Target: Peroxiredoxin 3 (PRDX3)

Hintergrund: Peroxiredoxin 3 is a mitochondrial protein belonging to the AhpC/TSA family. Expression of PRDX3 is induced by MYC and is reduced in c-myc -/- cells. Chromatin immunoprecipitation analysis spanning the entire PRDX3 genomic sequence revealed that MYC binds preferentially to a 930-bp region surrounding exon 1. Results using mitochondria-specific fluorescent probes demonstrated that Peroxiredoxin 3 is essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells.

UniProt: P30048

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process