NR4A3
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
The stated application concentrations are suggested starting amounts. Titration of the Tec antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
-20 °C
Informationen zur Lagerung
After reconstitution, the Tec antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Target
NR4A3
(Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))
CHN antikoerper, CSMF antikoerper, MINOR antikoerper, NOR1 antikoerper, TEC antikoerper, AI573420 antikoerper, NOR-1 antikoerper, Nor1 antikoerper, NOR-2 antikoerper, NR4A3 antikoerper, Nr4a3 antikoerper, nuclear receptor subfamily 4 group A member 3 antikoerper, nuclear receptor subfamily 4, group A, member 3 antikoerper, NR4A3 antikoerper, Nr4a3 antikoerper, nr4a3 antikoerper
Hintergrund
TEC Protein Tyrosine Kinase, is an enzyme that in humans is encoded by the TEC gene. The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. By fluorescence in situ hybridization, Sato et al.(1994) mapped the gene to 4p12, the same location reported for TXK. Mouse Tec is a non-receptor type protein-tyrosine kinase that is highly expressed in many hematopoietic cell lines. Hantschel et al.(2007) identified TEC kinase and BTK kinase as major binders of the tyrosine kinase inhibitor dasatinib, which is used for treatment of BCR/ABL-positive CML.