MPRIP Antikörper (N-Term)

Produktnummer ABIN3031920

Dieses Anti-MPRIP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MPRIP in WB. Geeignet für Human.

Kurzübersicht für MPRIP Antikörper (N-Term) (ABIN3031920)

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MPRIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MPRIP Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human RIP3 (EVKAMASLDNEFVLRLE) was used as the immunogen for this RIP3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the RIP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the RIP3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu MPRIP

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Andere Bezeichnung: RIP3

Hintergrund: Receptor-interacting serine/threonine-protein kinase 3(RIPK3), also known as RIP3, is an enzyme that in humans is encoded by the RIPK3 gene. This gene is mapped to 14q12. The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

UniProt: Q9Y572