MUC5AC Antikörper (AA 4848-5030)

Produktnummer ABIN3031872

Produktdetails anti-MUC5AC Antikörper

Target: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Bindungsspezifität: AA 4848-5030

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUC5AC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (4848-5030) was used as the immunogen for this MUC5AC antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the MUC5AC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the MUC5AC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu MUC5AC

Target: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Andere Bezeichnung: MUC5AC Mucin-5AC (MUC5AC Produkte)

Synonyme: MUC5 antikoerper, TBM antikoerper, leB antikoerper, 2210005L13Rik antikoerper, MGM antikoerper, mucin 5AC, oligomeric mucus/gel-forming antikoerper, putative gastric mucin antikoerper, mucin 5, subtypes A and C, tracheobronchial/gastric antikoerper, mucin 2, oligomeric mucus/gel-forming antikoerper, MUC5AC antikoerper, Smp_144070 antikoerper, Muc5ac antikoerper, MUC2 antikoerper

Hintergrund: Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. It is mapped to 11p15.5. MUC5AC is highly expressed in adult trachea and stomach. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease(COPD). It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold. It is also a direct and critical mediator of resistance during intestinal nematode infection.

Gen-ID: 4586