ANP32E Antikörper (C-Term)

Produktnummer ABIN303166

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ANP32E in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für ANP32E Antikörper (C-Term) (ABIN303166)

Target: ANP32E (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member E (ANP32E))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANP32E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ANP32E Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to amino acids close to carboxy terminus of human PHAP III.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Western Blot (0.5-2 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate Buffered Saline PBS, containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.

Details zu ANP32E

Target: ANP32E (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member E (ANP32E))

Andere Bezeichnung: ANP32E

Hintergrund: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.Synonyms: Acidic leucine-rich nuclear phosphoprotein 32 family member E, LANP-L, LANP-like protein, LANPL, PHAP III

Gen-ID: 81611

NCBI Accession: NP_001129950

UniProt: Q9BTT0