KLF3 Antikörper (N-Term)

Produktnummer ABIN3031564

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KLF3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für KLF3 Antikörper (N-Term) (ABIN3031564)

Target: KLF3 (Kruppel-Like Factor 3 (Basic) (KLF3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KLF3 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human KLF3 (SYPSNYMESMKPNKY) was used as the immunogen for this KLF3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the KLF3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the KLF3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu KLF3

Target: KLF3 (Kruppel-Like Factor 3 (Basic) (KLF3))

Andere Bezeichnung: KLF3

Hintergrund: Kruppel-like factor 3 is a protein that in humans is encoded by the KLF3 gene. It is also known as BKLF (Basic kruppel-like factor). KLF3 is a member of the Krüppel-like factors family of transcription factors. It primarily represses transcription through the transcriptional corepressor C-terminal binding protein (CtBP). Suske et al.(2005) stated that the human gene maps to chromosome 4p14, and the mouse gene maps to chromosome 5C3.3. Suske et al.(2005) stated that the human and mouse KLF3 proteins contain 345 and 344 amino acids, respectively. Both have a characteristic zinc finger domain, but lack the N-terminal buttonhead box found in related SP transcription factors. The repression mediated through KLF3 is also partially dependent on the sumoylation of its K10 and K197. Within KLF3's C-terminal, which is highly conserved throughout the KLF family, resides three C2H2 zinc fingers that preferentially bind the site NRG GNG NGR.

UniProt: P57682