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DCI Antikörper (C-Term)

ECI1 Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3030698
  • Target Alle DCI (ECI1) Antikörper anzeigen
    DCI (ECI1) (Enoyl-CoA Delta Isomerase 1 (ECI1))
    Bindungsspezifität
    • 11
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 41
    • 20
    • 11
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 38
    • 3
    Kaninchen
    Klonalität
    • 41
    Polyklonal
    Konjugat
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DCI Antikörper ist unkonjugiert
    Applikation
    • 34
    • 17
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Aufreinigung
    Antigen affinity
    Immunogen
    An amino acid sequence from the C-terminus of human DCI (ADVQNFVSFISKDSIQKSL) was used as the immunogen for this DCI antibody.
    Isotyp
    IgG
  • Applikationshinweise
    The stated application concentrations are suggested starting amounts. Titration of the DCI antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the DCI antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    DCI (ECI1) (Enoyl-CoA Delta Isomerase 1 (ECI1))
    Andere Bezeichnung
    DCI (ECI1 Produkte)
    Synonyme
    DCI antikoerper, Dci antikoerper, eci antikoerper, enoyl-CoA delta isomerase 1 antikoerper, enoyl-Coenzyme A delta isomerase 1 antikoerper, ECI1 antikoerper, Eci1 antikoerper
    Hintergrund
    Dodecenoyl-CoA Delta Isomerase, also known as 3,2-trans-enoyl-CoA isomerase (ECI1), is an enzyme that catalyzes the conversion of cis-or trans-double bonds of fatty acids at gamma-carbon(position 3) to trans double bonds at beta-carbon(position 2). It plays a particularly important role in the metabolism of unsaturated fatty acids. All classes of enoyl-CoA isomerases belong to a family of enzymes, the hydratase/isomerase or crotonase superfamily, and when examined with x-ray crystallography, exhibit a common structural feature of the family, the N-terminal core with a spiral fold composed of four turns, each turn consisting of two beta-sheets and one alpha-helix. Dodecenoyl-CoA Delta Isomerase/DCI is involved in the beta-oxidation, one of the most frequently used pathways in fatty acid degradation, of unsaturated fatty acids with double bonds at odd-numbered carbon positions. It does so by shifting the position of the double bonds in the acyl-CoA intermediates and converting 3-cis or trans-enoyl-CoA to 2-trans-enoyl-CoA.
    UniProt
    P42126
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