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CXCR4 Antikörper (AA 31-43)

Der Kaninchen Polyklonal Anti-CXCR4-Antikörper wurde für WB validiert. Er ist geeignet, CXCR4 in Proben von Human zu detektieren.
Produktnummer ABIN3030515

Kurzübersicht für CXCR4 Antikörper (AA 31-43) (ABIN3030515)

Target

Alle CXCR4 Antikörper anzeigen
CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reaktivität

  • 163
  • 91
  • 66
  • 21
  • 11
  • 10
  • 10
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 133
  • 36
  • 12
  • 9
  • 2
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 140
  • 53
  • 1
Polyklonal

Konjugat

  • 117
  • 9
  • 8
  • 7
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CXCR4 Antikörper ist unkonjugiert

Applikation

  • 128
  • 66
  • 56
  • 53
  • 35
  • 30
  • 26
  • 26
  • 25
  • 25
  • 9
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 16
    • 15
    • 15
    • 12
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-43

    Aufreinigung

    Antigen affinity

    Immunogen

    Amino acids 31-43 (EENANFNKIFLPT) were used as the immunogen for this CXCR4 antibody.

    Isotyp

    IgG
  • Applikationshinweise

    Titration of the CXCR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    Lagerung

    -20 °C

    Informationen zur Lagerung

    After reconstitution, the CXCR4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target

    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

    Andere Bezeichnung

    CXCR4

    Hintergrund

    Chemokine,CXC Motif, Receptor 4, also known as FUSIN or NPY3R, is a protein that in humans is encoded by the CXCR4 gene. By PCR analysis of human/hamster hybrid cell DNA, Herzog et al.(1993) showed that the NPY3R gene is located on human chromosome 2. Feng et al.(1996) showed that transient expression of the gene allowed nonhuman cells coexpressing recombinant CD4 to undergo Env-CD4-mediated cell fusion and productive HIV-1 infection. Peled et al.(1999) demonstrated that SDF1 and its receptor CXCR4 are critical for murine bone marrow engraftment by human SCID repopulating stem cells. Treatment of human cells with anti-CXCR antibodies prevented engraftment.

    UniProt

    P61073

    Pathways

    Regulation of Cell Size, CXCR4-mediated Signaling Events
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