BRSK1 Antikörper

Produktnummer ABIN303016

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BRSK1 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.Es wurde in 1 Publikation zitiert.

Kurzübersicht für BRSK1 Antikörper (ABIN303016)

Target: BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRSK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BRSK1 Antikörper

Spezifität: This antibody reacts to a 28 amino acid peptide from near the carboxy terminus of BRSK1.

Aufreinigung: Purified

Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot. Immunohistochemistry on paraffin sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline, containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-BRSK1 Antikörper (ABIN303016)

Zempel, Thies, Mandelkow, Mandelkow: "Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 36, pp. 11938-50, (2010) (PubMed).

Details zu BRSK1

Target: BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

Andere Bezeichnung: BRSK1

Hintergrund: BRSK1 is thought to be involved in the regulation of G2/M arrest and to function as a checkpoint kinase following DNA damage induced by UV or methyl methane sulfonate. BRSK1 phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.Synonyms: BR serine/threonine-protein kinase 1, KIAA1811, SAD-B, SAD1, SAD1 kinase, Serine/threonine kinase SAD-B

Gen-ID: 84446

NCBI Accession: NP_115806

UniProt: Q8TDC3