ABI2 Antikörper (N-Term)

Produktnummer ABIN3029825

Produktdetails anti-ABI2 Antikörper

Target: ABI2 (Abl-Interactor 2 (ABI2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human ABL Interactor 2 (RFKVSTQNMKMGGLPR) was used as the immunogen for this ABI2 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the ABI2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the ABI2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu ABI2

Target: ABI2 (Abl-Interactor 2 (ABI2))

Andere Bezeichnung: ABI2 (ABI2 Produkte)

Hintergrund: ABL Interactor 2 is a protein that in humans is encoded by the ABI2 gene. By analysis of a YAC and a BAC, Machado et al.(2000) mapped the gene to 2q31-q33. ABI2 possesses a basic N terminus with homology to a homeodomain protein, a central serine-rich region, three PEST sequences, which are implicated in susceptibility to protein degradation, several proline-rich stretches, and an acidic C terminus with multiple phosphorylation sites and an SH3 domain. Dai and Pendergast(1995) suggested that the ABI proteins may function to coordinate the cytoplasmic and nuclear functions of the ABL1 tyrosine kinase.

UniProt: Q9NYB9