Laminin Antikörper (AA 152-170)

Produktnummer ABIN3029737

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Laminin in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Laminin Antikörper (AA 152-170) (ABIN3029737)

Target: Laminin (LAMA2) (Laminin, alpha 2 (LAMA2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Laminin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Laminin Antikörper

Bindungsspezifität: AA 152-170

Aufreinigung: Antigen affinity

Immunogen: Amino acids 152-170 (WILERSLDDVEYKPWQYHA-human) were used as the immunogen for this LAMA2 antibody (100% mouse homology).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the LAMA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the LAMA2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Laminin

Target: Laminin (LAMA2) (Laminin, alpha 2 (LAMA2))

Andere Bezeichnung: LAMA2 Laminin 2 alpha

Hintergrund: Laminin 2 alpha is a protein that in humans is encoded by the LAMA2 gene. This gene is mapped to 6q22.33. Laminin, an extracellular protein, is a major component of the basement membrane. It is though to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

UniProt: P24043