Bcl-X/s (AA 120-130) Antikörper

Produktnummer ABIN3029688

Produktdetails

Target: Bcl-X/s

Bindungsspezifität: AA 120-130

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Amino acids 120-130 (YQSFEQDTFVE-human) were used as the immunogen for this Bcl-XS antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Bcl-XS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Bcl-XS antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Antigendetails

Target: Bcl-X/s

Andere Bezeichnung: Bcl-XS

Hintergrund: Bcl-XS is the second mRNA species of Bcl-X protein, which encodes a protein that inhibits the ability of Bcl-2 to enhance the survival of growth factor-deprived cells. In vivo, Bcl-XS mRNA is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. Apoptosis was associated with increased protein expression of Bcl-XS, an early marker of apoptosis, and release of Cytochrome C into the cytosol of infected HB cells.

UniProt: Q07817