CD3 epsilon Antikörper
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- Target Alle CD3 epsilon (CD3E) Antikörper anzeigen
- CD3 epsilon (CD3E)
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Reaktivität
- Human, Maus, Ratte, Schwein, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Hund, Schaf, Hamster, Huhn, Opossum, Primate, Cat, Cryptomys amatus (Mole rat), Elephant, Frosch
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD3 epsilon Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)
- Produktmerkmale
- This antibody recognizes the epsilon-chain of CD3 (CD3e), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the Tcell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the Tcell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the Tcell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the Tcell surface. CD3 antigen is a highly specific marker for Tcells, and is present in majority of Tcell neoplasms.
- Aufreinigung
- Protein A purified CD3e antibody
- Immunogen
- Amino acids ERPPPVPNPDYEP (156-168) were used as the immunogen for this CD3e antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product CD3E Primärantikörper
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- Applikationshinweise
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD3e antibody to be titered up or down for optimal performance.\. FACS: use the CD3e antibody at 0.5-1 μg/million cells,WB: 0.5-1.0 μg/mL,IP: 1-2 μg/500 μg protein lysate,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.2 mg/mL
- Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store the CD3e antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Target
- CD3 epsilon (CD3E)
- Andere Bezeichnung
- CD3e (CD3E Produkte)
- Synonyme
- cd3e antikoerper, CD3E antikoerper, t3e antikoerper, tcre antikoerper, AI504783 antikoerper, CD3 antikoerper, CD3epsilon antikoerper, T3e antikoerper, T3E antikoerper, TCRE antikoerper, CD3e molecule antikoerper, CD3 antigen, epsilon polypeptide antikoerper, cd3e antikoerper, CD3E antikoerper, Cd3e antikoerper
- Hintergrund
- This antibody recognizes the epsilon-chain of CD3 (CD3e), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the Tcell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the Tcell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the Tcell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the Tcell surface. CD3 antigen is a highly specific marker for Tcells, and is present in majority of Tcell neoplasms.
- Gen-ID
- 916
- Pathways
- T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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