CD1b Antikörper
Kurzübersicht für CD1b Antikörper (ABIN3026227)
Target
Alle CD1b (CD1B) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- PEG precipitation
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Immunogen
- Stimulated human leukocytes were used as the immunogen for the CD1b antibody.
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Isotyp
- IgM kappa
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Applikationshinweise
- Optimal dilution of the CD1b antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Functional Activity (Order SAF formulation)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the CD1b antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- CD1b (CD1B)
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Andere Bezeichnung
- CD1b
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Hintergrund
- The mouse monoclonal antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin (Workshop IV, Code T015). It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
Target
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