CD16 Antikörper
Kurzübersicht für CD16 Antikörper (ABIN3025888)
Target
Alle CD16 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- Human peripheral blood lymphocytes from a NK-leukemia patient were used as the immunogen for the CD16 antibody.
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Isotyp
- IgG2a kappa
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anti-CD16 (CD16) antibody
CD16 Reaktivität: Human, Non-Human Primate FACS, IP, IHC (fro) Wirt: Maus Monoclonal 3G8 unconjugated
anti-CD16 (CD16) antibodyCD16 Reaktivität: Human, Non-Human Primate FACS, IP Wirt: Maus Monoclonal LNK16 unconjugated
anti-CD16 (CD16) antibody (FITC)CD16 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal LNK16 FITC
anti-CD16 (CD16) antibodyCD16 Reaktivität: Human FACS, IP, WB, Func Wirt: Maus Monoclonal MEM-154 unconjugated
anti-CD16 (CD16) antibodyCD16 Reaktivität: Human, Schwein, Non-Human Primate FACS Wirt: Maus Monoclonal MEM-168 unconjugated
anti-CD16 (CD16) antibodyCD16 Reaktivität: Human FACS, IP, WB Wirt: Maus Monoclonal MEM-154 unconjugated
anti-CD16 (CD16) antibody (Biotin)CD16 Reaktivität: Human FACS, IP, WB Wirt: Maus Monoclonal MEM-154 Biotin
anti-CD16 (CD16) (AA 17-208) antibodyCD16 Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 2G10A9 unconjugated
anti-CD16 (CD16) antibodyCD16 Reaktivität: Human, Non-Human Primate FACS, IP, Func, IHC (fro) Wirt: Maus Monoclonal 3G8 unconjugated
anti-CD16 (CD16) antibodyCD16 Reaktivität: Human FACS Wirt: Maus Monoclonal GRM1 unconjugated
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Applikationshinweise
- Optimal dilution of the CD16 antibody should be determined by the researcher.\. Functional Activity (Order SAF formulation),Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the CD16 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- CD16
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Andere Bezeichnung
- CD16
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Hintergrund
- Recognizes a protein of 50-65 kDa, identified as CD16 (Workshop IV, Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This mAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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