CX3CR1 Antikörper (3rd Extracellular Domain)

Produktnummer ABIN302578

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CX3CR1 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CX3CR1 Antikörper (3rd Extracellular Domain) (ABIN302578)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CX3CR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CX3CR1 Antikörper

Bindungsspezifität: 3rd Extracellular Domain

Spezifität: This antinody detects CX3C Chemokine Fractalkine Receptor 1 (CX3CR1) at 3rd extracellular domain.

Aufreinigung: Immunoaffinity chromatography

Immunogen: CX3CR1 antibody was raised against synthetic peptide from 3rd extracellular domain of human CX3CR1.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections (3.8 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Details zu CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Andere Bezeichnung: CX3CR1 / GPR13

Hintergrund: CX3CR1 a Chemokine Receptor is an HIV coreceptor, as well as a leukocyte chemotactic/adhesion receptor for fractalkine, also known as neurotactin. CX3CR1 mediates chemotactic responses to the soluble form of fractalkine in neutrophils and T cells, and cytoadhesion to cells expressing membrane-anchored fractalkine, such as monocytes, T cells, and neutrophils. Cells transfected with CX3CR1 exhibited chemotaxis and transient increases in intracellular calcium concentration when exposed to fractalkine.Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28

Gen-ID: 1524

NCBI Accession: NP_001164642

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin