CD28 Antikörper
Kurzübersicht für CD28 Antikörper (ABIN3025653)
Target
Alle CD28 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD28 Antibody (azide and preservative free)
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- Stimulated human leukocytes were used as the immunogen for the CD28 antibody.
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Optimal dilution of the CD28 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the CD28 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CD28
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Andere Bezeichnung
- CD28
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Hintergrund
- Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
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UniProt
- P10747
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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