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ODC1 Antikörper

Der Maus Monoklonal Anti-ODC1-Antikörper wurde für WB, IF, FACS und IHC (p) validiert. Er ist geeignet, ODC1 in Proben von Human und Ratte zu detektieren.
Produktnummer ABIN3025563

Kurzübersicht für ODC1 Antikörper (ABIN3025563)

Target

Alle ODC1 Antikörper anzeigen
ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reaktivität

  • 96
  • 53
  • 35
  • 15
  • 15
  • 1
  • 1
Human, Ratte

Wirt

  • 66
  • 37
  • 2
Maus

Klonalität

  • 62
  • 43
Monoklonal

Konjugat

  • 53
  • 8
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ODC1 Antikörper ist unkonjugiert

Applikation

  • 86
  • 31
  • 30
  • 24
  • 21
  • 20
  • 18
  • 14
  • 13
  • 13
  • 13
  • 4
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

ODC1-487
  • Aufreinigung

    Protein G affinity chromatography

    Immunogen

    Recombinant human protein was used as the immunogen for the Ornithine Decarboxylase antibody.

    Isotyp

    IgG2a kappa
  • Applikationshinweise

    Optimal dilution of the Ornithine Decarboxylase antibody should be determined by the researcher.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1),Prediluted format: incubate for 30 min at RT (2)

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Konservierungsmittel

    Azide free

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store the Ornithine Decarboxylase antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target

    ODC1 (Ornithine Decarboxylase 1 (ODC1))

    Andere Bezeichnung

    Ornithine Decarboxylase

    Hintergrund

    Recognizes a 53  kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
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